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gamma Sarcoglycan antibody

GTX117176
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetSGCG
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Overview

  • Supplier
    GeneTex
  • Product Name
    gamma Sarcoglycan antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6445
  • Target name
    SGCG
  • Target description
    sarcoglycan gamma
  • Target synonyms
    35 kDa dystrophin-associated glycoprotein; 35DAG; 35kD dystrophin-associated glycoprotein; A4; DAGA4; DMDA; DMDA1; gamma-sarcoglycan; gamma-SG; LGMD2C; LGMDR5; MAM; sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein); SCARMD2; SCG3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13326
  • Protein Name
    Gamma-sarcoglycan
  • Scientific Description
    This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sarcospan increases laminin-binding capacity of alpha-dystroglycan to ameliorate DMD independent of Galgt2.
    Read more
  • Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration. Perez-Ortiz AC et al., 2019 Nov 4, Int J Mol Sci
    Read more
  • Effects of (-)-epicatechin on frontal cortex DAPC and dysbindin of the mdx mice. Estrada-Mena FJ et al., 2017 Sep 29, Neurosci Lett
    Read more

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