gamma-Secretase modulator 11 (hydrochloride) [2434630-30-3]
HY-147720A
Overview
- SupplierMedChem Express
- Product Namegamma-Secretase modulator 11 (hydrochloride) [2434630-30-3]
- Delivery Days Customer10
- CAS Number2434630-30-3
- CertificationResearch Use Only
- Molecular FormulaC28H23ClF2N4O2
- Molecular Weight520.96
- Scientific Descriptiongamma-Secretase modulator 11 hydrochloride (compound 1o) is a potent and orally active gamma-secretase modulator with an IC50 of 0.029 microM. gamma-Secretase modulator 11 hydrochloride induces a robust reduction in brain Abeta42 levels. gamma-Secretase modulator 11 hydrochloride rescues cognitive deficits exhibited by AD model mice. gamma-Secretase modulator 11 hydrochloride has the potential for the research of alzheimers disease[1].
- SMILESO=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=C(F)C=C5)C=C4F)=CC=CN32)C=C1)NC.[H]Cl
- UNSPSC12131703