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ProductsBack/gamma-Secretase modulator 11 (hydrochloride) [2434630-30-3]

gamma-Secretase modulator 11 (hydrochloride) [2434630-30-3]

HY-147720A
MedChem Express
CAS Number2434630-30-3
Product group Chemicals
Molecular Weight520.96
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Overview

  • Supplier
    MedChem Express
  • Product Name
    gamma-Secretase modulator 11 (hydrochloride) [2434630-30-3]
  • Delivery Days Customer
    10
  • CAS Number
    2434630-30-3
  • Certification
    Research Use Only
  • Molecular Formula
    C28H23ClF2N4O2
  • Molecular Weight
    520.96
  • Scientific Description
    gamma-Secretase modulator 11 hydrochloride (compound 1o) is a potent and orally active gamma-secretase modulator with an IC50 of 0.029 microM. gamma-Secretase modulator 11 hydrochloride induces a robust reduction in brain Abeta42 levels. gamma-Secretase modulator 11 hydrochloride rescues cognitive deficits exhibited by AD model mice. gamma-Secretase modulator 11 hydrochloride has the potential for the research of alzheimers disease[1].
  • SMILES
    O=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=C(F)C=C5)C=C4F)=CC=CN32)C=C1)NC.[H]Cl
  • UNSPSC
    12131703

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