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Ganciclovir triphosphate [86761-38-8]

HY-131605
MedChem Express
CAS Number86761-38-8
Product group Chemicals
Molecular Weight495.17
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ganciclovir triphosphate [86761-38-8]
  • Delivery Days Customer
    9
  • CAS Number
    86761-38-8
  • Certification
    Research Use Only
  • Molecular Formula
    C9H16N5O13P3
  • Molecular Weight
    495.17
  • Scientific Description
    Ganciclovir triphosphate (GCV-TP) is a synthetic 2-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate has an IC50 of 0.01 microM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition[1].
  • SMILES
    O=P(O)(OP(O)(OP(O)(O)=O)=O)OCC(OCN1C=NC2=C1N=C(N)NC2=O)CO
  • UNSPSC
    12352200