Ganciclovir triphosphate [86761-38-8]
HY-131605
CAS Number86761-38-8
Product group Chemicals
Molecular Weight495.17
Overview
- SupplierMedChem Express
- Product NameGanciclovir triphosphate [86761-38-8]
- Delivery Days Customer9
- CAS Number86761-38-8
- CertificationResearch Use Only
- Molecular FormulaC9H16N5O13P3
- Molecular Weight495.17
- Scientific DescriptionGanciclovir triphosphate (GCV-TP) is a synthetic 2-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate has an IC50 of 0.01 microM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition[1].
- SMILESO=P(O)(OP(O)(OP(O)(O)=O)=O)OCC(OCN1C=NC2=C1N=C(N)NC2=O)CO
- UNSPSC12352200
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