Gandotinib [1229236-86-5]

TargetMol Chemicals

Gandotinib [1229236-86-5]

4

1229236-86-5

Chemical

Research Use Only

Gandotinib

99.86%

C23H25ClFN7O

469.94

LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.

3 years

C(C=1C=2N(C(CC3=C(F)C=C(Cl)C=C3)=C(C)N2)N=C(NC=4C=C(C)NN4)C1)N5CCOCC5

-20°C

12352200