Ganoderic acid D

MedChem Express

Ganoderic acid D [108340-60-9]

10

108340-60-9

Research Use Only

99.40

C30H42O7

514.65

Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum . Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells [1] . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis [2] .

CC1(C)C(CC[C@]2(C)C3=C([C@@]4(C(C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(CC(C)C(O)=O)=O)=O)C)[C@@H](O)C[C@@]12[H])=O

-20°C,2°C to 8°C

12352200