GANT61

AbMole BioScience

GANT61

9

500579-04-4

Chemical

Research Use Only

C27H35N5

429.6

GANT61 is a Gli1 and Gli2 inhibitor targeting the Hedgehog/GLi pathway that inhibits GLI1- and GLI2-induced transcription with an IC50 of 5 uM. In addition, GANT61 selectively acts on the transcription of other pathways such as TNF and glucocorticoid receptor genes.

Benzenamine, 2,2'-[[dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-

12352200