Garcinol [78824-30-3]

MedChem Express

Garcinol [78824-30-3]

5

78824-30-3

Research Use Only

99.0

C38H50O6

602.80

Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 microM and 7.39 microM, respectively[1]. Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 microM) and p300/CPB-associated factor (PCAF, IC50 = 5 microM). Garcinol has anti-inflammatory and anti-cancer activity[2].

C/C(C)=C\C[C@@H](C[C@]12C([C@](C(C)([C@@H](C2)C/C=C(C)\C)C)(C/C=C(C)\C)C(C(C(C3=CC(O)=C(C=C3)O)=O)=C1O)=O)=O)C(C)=C

-20°C

12131703