GBR 12935 (dihydrochloride) [67469-81-2]

MedChem Express

GBR 12935 (dihydrochloride) [67469-81-2]

10

67469-81-2

Research Use Only

99.80

C28H36Cl2N2O

487.50

GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 dihydrochloride stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 dihydrochloride also prevents the d-Fenfluramine-induced head-twitch response in mice[1][2][3][4].

N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(CCCC4=CC=CC=C4)CC1.Cl.Cl

2°C to 8°C

12352200