Gcase activator 3 [2270984-21-7]

TargetMol Chemicals

Gcase activator 3 [2270984-21-7]

16

Research Use Only

C23H20N4O2

384.43

GCase activator 3 (compound 9Q) is a glucosidase (Glucosidase, GCase) activator that enhances GCase activity by partially stabilizing the enzyme. It reduces misfolding and degradation of mutant GCase protein in fibroblasts and dopaminergic midbrain neurons. This compound is applicable in the study of Parkinsons disease (PD) and related synucleinopathies [1].

N(C[C@@H]1OC=2C(OC1)=CC=CC2)(C)C=3C4=C(N=C(N3)C=5C=CC=NC5)C=CC=C4

-20°C

51202000