GCKR, Human (P.pastoris, His)

MedChem Express

GCKR, Human (P.pastoris, His)

10

Research Use Only

90.00

GCKR

glucokinase regulator

FGQTL5; GKRP; glucokinase (hexokinase 4) regulator; glucokinase regulatory protein; hexokinase 4 regulator

Glucokinase regulatory protein

The GCKR protein plays a critical regulatory role in glucokinase (GCK) by forming an inactive complex and recruiting GCK to the nucleus after meals. Its interaction with GCK is finely tuned by fructose metabolites; binding of GCKR to fructose-6-phosphate increases the affinity for GCK, whereas binding to fructose-1-phosphate decreases the affinity, thereby releasing inhibition. GCKR Protein, Human (P.pastoris, His) is the recombinant human-derived GCKR protein, expressed by P. pastoris , with N-His labeled tag.

-20°C

41116100