GCN2 activator-1 [315705-10-3]
HY-W319647
CAS Number315705-10-3
Product group Chemicals
Molecular Weight290.37
Overview
- SupplierMedChem Express
- Product NameGCN2 activator-1 [315705-10-3]
- Delivery Days Customer999
- CAS Number315705-10-3
- CertificationResearch Use Only
- Molecular FormulaC11H10N6S2
- Molecular Weight290.37
- Scientific DescriptionGCN2 activator-1 (Compound 20) is a GCN2 activator. GCN2 activator-1 binds within the ATP-pocket of GCN2 and activates GCN2 in a GCN1-independent manner. GCN2 activator-1 activates Integrated Stress Response (ISR) in cells. GCN2 activator-1 inhibits PKR with an IC50 of 3.75 microM. GCN2 activator-1 can be used for research of pulmonary veno-occlusive disease (PVOD)[1].
- SMILESNC1=NC(C)=C(C2=CSC(NC3=NC=CC=N3)=N2)S1
- UNSPSC12352200