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GCN2-IN-6 [2183470-09-7]

GCN2-IN-6 [2183470-09-7]

T11374
TargetMol Chemicals
CAS Number2183470-09-7
Product group Chemicals
Estimated Purity97.97%
Molecular Weight485.29
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GCN2-IN-6 [2183470-09-7]
  • Delivery Days Customer
    10
  • CAS Number
    2183470-09-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GCN2-IN-6
  • Estimated Purity
    97.97%
  • Molecular Formula
    C19H12Cl2F2N4O3S
  • Molecular Weight
    485.29
  • Scientific Description
    GCN2-IN-6 is a potent and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50: 1.8 nM) and cellular assays (IC50: 9.3 nM). GCN2-IN-6 is also an eIF2alpha kinase PERK inhibitor with IC50s of 0.26 nM in enzymatic assay and 230 nM in cells respectively.
  • Shelf life instruction
    3 years
  • SMILES
    Nc1ncc(cn1)C#Cc1c(F)ccc(NS(=O)(=O)c2cc(Cl)cc(CO)c2Cl)c1F
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

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