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GDC-0276 [1494581-70-2]

GDC-0276 [1494581-70-2]

T11377
TargetMol Chemicals
CAS Number1494581-70-2
Product group Chemicals
Molecular Weight462.58
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GDC-0276 [1494581-70-2]
  • Delivery Days Customer
    72
  • CAS Number
    1494581-70-2
  • Certification
    Research Use Only
  • Chemical Name
    GDC-0276
  • Molecular Formula
    C24H31FN2O4S
  • Molecular Weight
    462.58
  • Scientific Description
    GDC-0276, a potent, selective, reversible, and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM, offers potential for pain treatment while overcoming limitations associated with current pain medications, including addiction and off-target side effects. It is well tolerated and demonstrates a favorable pharmacokinetic profile.
  • Shelf life instruction
    3 years
  • SMILES
    Fc1cc(OCC23CC4CC(CC(C4)C2)C3)c(cc1C(=O)NS(=O)(=O)N1CCC1)C1CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200