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GDC-0339 [1428569-85-0]

Research Use Only
T15376
TargetMol Chemicals
CAS Number1428569-85-0
Product group Chemicals
Molecular Weight465.5
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    GDC-0339 [1428569-85-0]
  • Delivery Days Customer
    114
  • CAS Number
    1428569-85-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    GDC-0339
  • Molecular Formula
    C20H22F3N7OS
  • Molecular Weight
    465.5
  • Scientific Description
    GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively).
  • Shelf life instruction
    3 years
  • SMILES
    Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@H](N)[C@H](F)CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Takahashi RH, et al. CYP1A1-Mediated Intramolecular Rearrangement of Aminoazepane in GDC-0339. Drug Metab Dispos. 2017 Oct;45(10):1084-1092.
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