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GDC-0339 [1428569-85-0]
T15376
Overview
- SupplierTargetMol Chemicals
- Product NameGDC-0339 [1428569-85-0]
- Delivery Days Customer114
- CAS Number1428569-85-0
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameGDC-0339
- Molecular FormulaC20H22F3N7OS
- Molecular Weight465.5
- Scientific DescriptionGDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively).
- Shelf life instruction3 years
- SMILESCn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@H](N)[C@H](F)CC1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Takahashi RH, et al. CYP1A1-Mediated Intramolecular Rearrangement of Aminoazepane in GDC-0339. Drug Metab Dispos. 2017 Oct;45(10):1084-1092.Read more