GDC-0623
M14169
CAS Number1168091-68-6
Product group Chemicals
Molecular Weight456.21
Overview
- SupplierAbMole BioScience
- Product NameGDC-0623
- Delivery Days Customer9
- CAS Number1168091-68-6
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular Weight456.21
- Scientific DescriptionGDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM).
- SMILESOCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)[N]3C=NC=C3C=C1
- UNSPSC12352200