GDC0575 monohydrochloride [1196504-54-7]
T27407
CAS Number1196504-54-7
Product group Chemicals
Estimated Purity97.85%
Molecular Weight414.73
Overview
- SupplierTargetMol Chemicals
- Product NameGDC0575 monohydrochloride [1196504-54-7]
- Delivery Days Customer4
- CAS Number1196504-54-7
- CertificationResearch Use Only
- Chemical NameGDC0575 monohydrochloride
- Estimated Purity97.85%
- Molecular FormulaC16H21BrClN5O
- Molecular Weight414.73
- Scientific DescriptionGDC0575 monohydrochloride (ARRY575) is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.
- Shelf life instruction3 years
- SMILESO=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32.[H]Cl
- Storage Instruction-20°C
- UNSPSC12352200
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GDC0575 (hydrochloride) [1196504-54-7]HY-112167B
CAS Number1196504-54-7
Molecular Weight414.73
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Product group Chemicals
GDC0575 monohydrochlorideORB1305087
CAS Number1196504-54-7
Estimated Purity97.85%
Molecular Weight414.73
- SizePrice