GDF-15, Cynomolgus (His)

MedChem Express

GDF-15, Cynomolgus (His)

10

Research Use Only

GDF15

growth differentiation factor 15

growth/differentiation factor 15

Growth/differentiation factor 15

GDF-15 Protein, a key regulator of food intake and energy balance, binds to its receptor GFRAL, activating neurons in the brainstem and forming an emergency circuit for feeding responses during stress. Additionally, GDF-15 inhibits growth hormone signaling on hepatocytes, existing as a disulfide-linked homodimer. Interacting with GFRAL, it acts as a ligand, mediating GDF15 internalization and cellular signaling through RET. GDF-15 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived GDF-15 protein, expressed by E. coli , with N-His labeled tag.

41116100

Primate