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GDF-15, Human (P.pastoris, His)

HY-P75170
MedChem Express
Protein IDQ99988
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GDF-15, Human (P.pastoris, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    97.00
  • Protein IDQ99988
  • Protein Name
    Growth/differentiation factor 15
  • Scientific Description
    Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor beta (TGF-beta) superfamily. GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1), placental transforming growth factor-beta (PTGFB), prostate-derived factor (PDF), and placental bone morphogenetic protein (PLAB). GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging, cancer, and metabolic processes. GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET, AKT, ERK1/2, and phospholipase C (PLCgamma)[1]. GDF-15 Protein, Human (P.pastoris, His) has 112 amino acids expressed by P.pastoris yeast cells with N-terminal His tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202

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