GDF-15, Mouse (HEK293, hFc)

MedChem Express

GDF-15, Mouse (HEK293, hFc)

5

Research Use Only

95.00

Gdf15

growth differentiation factor 15

MIC-1, NAG-1, SBF, growth/differentiation factor 15, macrophage inhibiting cytokine-1, macrophage inhibitory cytokine 1

Growth/differentiation factor 15

Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor beta (TGF-beta) superfamily. GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1), placental transforming growth factor-beta (PTGFB), prostate-derived factor (PDF), and placental bone morphogenetic protein (PLAB). GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging, cancer, and metabolic processes. GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET, AKT, ERK1/2, and phospholipase C (PLCgamma)[1]. GDF-15 Protein, Mouse (HEK293, hFc) has 115 amino acids expressed by HEK293 cells with N-terminal hFc tag.

-20°C

41116100