GDF5 antibody [13J15]

GeneTex

GDF5 antibody [13J15]

9

WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, Neutralisation/Blocking

Research Use Only

Monoclonal

13J15

500 ug/ml

Unconjugated

Gdf5

growth differentiation factor 5

BMP-14, Cdmp-1, bp, brp, growth/differentiation factor 5, bone morphogenetic protein 14, cartilage-derived morphogenetic protein-1

Rat

IgG2

Growth/differentiation factor 5

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mice with a mutation in this gene exhibit enhanced tooth enamel formation. [provided by RefSeq, Aug 2016]

Mouse

-20°C or -80°C,2°C to 8°C

41116161