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ProductsBack/GDF5 antibody

GDF5 antibody

Research Use Only
GTX113580
GeneTex
ApplicationsFunctional Assay, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetGDF5
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Overview

  • Supplier
    GeneTex
  • Product Name
    GDF5 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Functional Assay, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.65 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID8200
  • Target name
    GDF5
  • Target description
    growth differentiation factor 5
  • Target synonyms
    BDA1C; BMP14; BMP-14; bone morphogenetic protein 14; cartilage-derived morphogenetic protein-1; CDMP1; DUPANS; growth/differentiation factor 5; LAP4; LAP-4; lipopolysaccharide-associated protein 4; LPS-associated protein 4; OS5; radotermin; SYM1B; SYNS2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP43026
  • Protein Name
    Growth/differentiation factor 5
  • Scientific Description
    The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Nonviral Gene Delivery of Growth and Differentiation Factor 5 to Human Mesenchymal Stem Cells Injected into a 3D Bovine Intervertebral Disc Organ Culture System. Bucher C et al., 2013, Stem Cells Int
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  • GDF5 regulates TGFbeta-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFbeta peptides. Margheri F et al., 2012, PLoS One
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