The data was published in the journal PLoS One in 2015.PMID: 25875253
The data was published in the journal PLoS One in 2015.PMID: 25875253
GDF8 / Myostatin antibody [13F2]
GTX53334
Overview
- SupplierGeneTex
- Product NameGDF8 / Myostatin antibody [13F2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID13F2
- Concentration500 ug/ml
- ConjugateUnconjugated
- Gene ID17700
- Target nameMstn
- Target descriptionmyostatin
- Target synonymsCmpt; Gdf8; growth/differentiation factor 8
- HostRat
- IsotypeIgG2
- Protein IDO08689
- Protein NameGrowth/differentiation factor 8
- Scientific DescriptionThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Homozygous knockout mice for this gene exhibit increased muscle mass and bone density, and reduced adiposity. [provided by RefSeq, Jul 2016]
- ReactivityMouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Dual roles of palladin protein in in vitro myogenesis: inhibition of early induction but promotion of myotube maturation. Nguyen NU et al., 2015, PLoS OneRead more