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Gedatolisib

HY-10681
MedChem Express
CAS Number1197160-78-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.68
Molecular Weight615.73
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Gedatolisib [1197160-78-3]
  • Delivery Days Customer
    10
  • CAS Number
    1197160-78-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.68
  • Molecular Formula
    C32H41N9O4
  • Molecular Weight
    615.73
  • Scientific Description
    Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kalpha , PI3Kgamma , and mTOR with IC 50 s of 0.4 nM, 5.4 nM and 1.6 nM, respectively [1] . Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2 [2] .
  • SMILES
    CN(C1CCN(C(C2=CC=C(NC(NC3=CC=C(C4=NC(N5CCOCC5)=NC(N6CCOCC6)=N4)C=C3)=O)C=C2)=O)CC1)C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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