Gefapixant [1015787-98-0]

MedChem Express

Gefapixant [1015787-98-0]

10

1015787-98-0

Research Use Only

99.93

C14H19N5O4S

353.40

Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis[1][2][3].

O=S(C1=CC(OC2=CN=C(N)N=C2N)=C(C(C)C)C=C1OC)(N)=O

-20°C,2°C to 8°C

12352200