Gefitinib (Standard) [184475-35-2]
HY-50895R
Product group Assays
Overview
- SupplierMedChem Express
- Product NameGefitinib (Standard) [184475-35-2]
- Delivery Days Customer5
- CAS Number184475-35-2
- CertificationResearch Use Only
- Molecular FormulaC22H24ClFN4O3
- Molecular Weight446.90
- Scientific DescriptionGefitinib (Standard) is the analytical standard of Gefitinib. This product is intended for research and analytical applications. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer [1][2][5].
- SMILESClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F
- UNSPSC41116135