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Chemical Structure
Chemical Structure
Chemical Structure

Geldanamycin

BVT-0196
BioViotica
CAS Number30562-34-6
Product group Chemicals
Estimated Purity>98%
Molecular Weight560.6
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Overview

  • Supplier
    BioViotica
  • Product Name
    Geldanamycin [30562-34-6]
  • Delivery Days Customer
    10
  • CAS Number
    30562-34-6
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Warning
  • Molecular Formula
    C29H40N2O9
  • Molecular Weight
    560.6
  • Scientific Description
    Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor. - Chemical. CAS: 30562-34-6. Formula: C29H40N2O9. MW: 560.6. Isolated from Streptomyces hygroscopicus. Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor.
  • SMILES
    CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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