Gemcitabine

AbMole BioScience

Gemcitabine

9

95058-81-4

Chemical

Research Use Only

1

C9H11F2N3O4

263.2

Gemcitabine (LY-188011; NSC 613327) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis.

NC1=NC(=O)N(C=C1)C2OC(CO)C(O)C2(F)F

-20°C, protect from light, sealed

12352200