Gemin2 antibody [2E17]

GeneTex

Gemin2 antibody [2E17]

9

Human Gemin2. Detects a band of approximately 34 kDa. Cross reacts with xenopus

Optimal dilutions should be determined experimentally by the researcher.

2E17

Liquid

GEMIN2

gem nuclear organelle associated protein 2

component of gems 2; gem-associated protein 2; gemin-2; SIP1; SIP1-delta; SMN interacting protein 1-delta; survival of motor neuron protein interacting protein 1

Gem-associated protein 2

This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]

-20°C or -80°C,2°C to 8°C

12352203