Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA823902LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA823902LA01HU at dilution of 1:100
GEMIN6 Antibody
CSB-PA823902LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetGEMIN6
Overview
- SupplierCusabio
- Product NameGEMIN6 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79833
- Target nameGEMIN6
- Target descriptiongem nuclear organelle associated protein 6
- Target synonymsgem-associated protein 6; gemin-6; SIP2
- HostRabbit
- IsotypeIgG
- Protein IDQ8WXD5
- Protein NameGem-associated protein 6
- Scientific DescriptionThe SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203