GFB-12811 [2775311-17-4]

TargetMol Chemicals

GFB-12811 [2775311-17-4]

10

Research Use Only

GFB-12811

C22H23F4N5O

449.44

GFB-12811 is a highly selective and orally active inhibitor of cyclin-dependent kinase 5 (CDK5), exhibiting an inhibitory concentration (IC50) of 2.3 nM. It demonstrates notable specificity, with minimal activity against other tested kinases, including CDK1, CDK2, CDK6, CDK7, and CDK9 [1].

3 years

[C@](C)(O)(C1=NC2=C(C=C1)C=NC(NC=3C=C(C(F)(F)F)N=CC3F)=C2)C4CCN(C)CC4

-20°C

12352200