GFB-8438 [2304549-73-1]
HY-133012
CAS Number2304549-73-1
Product group Chemicals
Estimated Purity98.41
Molecular Weight386.76
Overview
- SupplierMedChem Express
- Product NameGFB-8438 [2304549-73-1]
- Delivery Days Customer9
- CAS Number2304549-73-1
- CertificationResearch Use Only
- Estimated Purity98.41
- Molecular FormulaC16H14ClF3N4O2
- Molecular Weight386.76
- Scientific DescriptionGFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0.18 and 0.29 microM of hTRPC5 and hTRPC4, respectively. GFB-8438 shows excellent selectivity against TRPC6, other TRP family members, NaV 1.5, as well as limited activity against the hERG channel. GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model[1].
- SMILESO=C1CN(C2=C(Cl)C(NN=C2)=O)CCN1CC3=CC=CC=C3C(F)(F)F
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200