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GFB-8438

M10927
AbMole BioScience
CAS Number2304549-73-1
Product group Chemicals
Molecular Weight386.76
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    GFB-8438
  • Delivery Days Customer
    9
  • CAS Number
    2304549-73-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C16H14ClF3N4O2
  • Molecular Weight
    386.76
  • Scientific Description
    GFB-8438 is a potent subtype selective TRPC5 inhibitor against hTRPC5 and hTRPC4 IC50 0.18 and 0.29 uM, respectively. GFB-8438 has good selectivity for TRPC6, other members of the TRP family, NaV1.5, and limited activity against hERG channels. Protective effect of GFB-8438 on mouse podocytes.
  • SMILES
    FC(F)(F)C1=CC=CC=C1CN2CCN(CC2=O)C3=C(Cl)C(=O)NN=C3
  • UNSPSC
    12352200