GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi)

TargetMol Chemicals

GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi)

16

Research Use Only

40.7 kDa (predicted). Due to glycosylation, the protein migrates to 48-62 kDa based on Tris-Bis PAGE result.

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 40.7 kDa and the accession number is Q6UXV0.

-20°C

12352200