GGTI-2154 (hydrochloride)

MedChem Express

GGTI-2154 (hydrochloride) [478908-50-8]

10

478908-50-8

Research Use Only

98.93

C24H29ClN4O3

456.97

GGTI-2154 hydrochloride is a potent and selective inhibitor geranylgeranyltransferase I (GGTase I) , with an IC 50 of 21 nM. GGTI-2154 hydrochloride shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM). GGTI-2154 hydrochloride can be used for the research of cancer [1] [2] .

CC(C)C[C@@H](C(O)=O)NC(C1=CC=C(NCC2=CN=CN2)C=C1C3=CC=CC=C3C)=O.[H]Cl

2°C to 8°C

12352200