GGTI-286 [171744-11-9]

TargetMol Chemicals

GGTI-286 [171744-11-9]

72

171744-11-9

Research Use Only

GGTI-286

C23H31N3O3S

429.58

GGTI-286 is a potent, cell permeable GGTase I inhibitor (IC50: 2 microM). GGTI-286 inhibits Rap1A geranylation in NIH3T3 cells (IC50: 2 microM) more potently than H-Ras farnesylation (IC50>30 microM). Ras4B stimulation (IC50: 1 microM).

3 years

C(N[C@H](C(OC)=O)CC(C)C)(=O)C1=C(C=C(NC[C@H](CS)N)C=C1)C2=CC=CC=C2

-20°C

12352200