Dendrobium phenol [67884-30-4]

TargetMol Chemicals

Gigantol [67884-30-4]

4

67884-30-4

Chemical

Research Use Only

Gigantol

99.48%

C16H18O4

274.31

Gigantol is a novel inhibitor of the Wnt/beta-catenin pathway. It inhibits Wnt/beta-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic beta-catenin in breast cancer cells. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows the protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-kappaB signaling pathway.Gigantol also shows alpha-glucosidase inhibitory activity.

3 years

COc1cc(O)cc(CCc2ccc(OC)c(O)c2)c1

-20°C

12352200