Giredestrant

MedChem Express

Giredestrant [1953133-47-5]

9

1953133-47-5

99.52

C27H31F5N4O

522.55

Giredestrant (GDC-9545), a non-steroidal estrogen receptor (ER) ligand, is an orally active and selective ER antagonist. Giredestrant potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity [1] .

OCC(F)(F)CN([C@@H]1C2=C(F)C=C(NC3CN(CCCF)C3)C=C2F)[C@H](C)CC4=C1NC5=C4C=CC=C5

-20°C,2°C to 8°C

12352200