Giredestrant (tartrate)

Biorbyt

Giredestrant (tartrate) [2407529-33-1]

10

2407529-33-1

Research Use Only

C31N4O7F5H37

672.6401

Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation.

FC(C([H])([H])O[H])(C([H])([H])N1[C@]([H])(C([H])([H])[H])C([H])([H])C2C3=C([H])C([H])=C([H])C([H])=C3N([H])C=2[C@@]1([H])C1C(=C([H])C(=C([H])C=1F)N([H])C1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])F)C1([H])[H])F)F.O([H])[C@@]([H])(C(=O)O[H])[C@]([H])(C(=O)O[H])O[H]

12352200