GITR (mouse):Fc (human) (rec.)

AdipoGen Life Sciences

GITR (mouse):Fc (human) (rec.)

10

Research Use Only

1 mg/ml

>95%

Tnfrsf18

tumor necrosis factor receptor superfamily, member 18

AITR, Gitr, tumor necrosis factor receptor superfamily member 18, glucocorticoid-induced TNFR-related protein

Tumor necrosis factor receptor superfamily member 18

GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway. - Protein. Mouse GITR (aa 20-152) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway.

-20°C,2°C to 8°C

41116100

Mouse