GKT136901

MedChem Express

GKT136901 [955272-06-7]

10

955272-06-7

Research Use Only

99.70

C19H15ClN4O2

366.80

GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4) , with K i s of 160 and 165 nM, respectively. GKT136901 is also a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity [1] [2] [3] .

O=C1N(C2=CC=CC=C2Cl)NC(C1=C(C)N3CC4=NC=CC=C4)=CC3=O

-20°C,2°C to 8°C

12352200