GKT136901 (hydrochloride)

MedChem Express

GKT136901 (hydrochloride) [1254507-01-1]

10

1254507-01-1

Research Use Only

99.90

C19H16Cl2N4O2

403.26

GKT136901 hydrochloride is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4) , with K i s of 160 and 165 nM, respectively. GKT136901 hydrochloride is also a selective and direct scavenger of peroxynitrite. GKT136901 hydrochloride can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 hydrochloride also has anti-inflammatory activity [1] [2] [3] .

O=C1N(C2=CC=CC=C2Cl)NC(C1=C(C)N3CC4=NC=CC=C4)=CC3=O.[H]Cl

2°C to 8°C

12352200