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Glafenine (hydrochloride) (Standard) [65513-72-6]

HY-B1153AR
MedChem Express
CAS Number65513-72-6
Product group Chemicals
Molecular Weight409.26
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Glafenine (hydrochloride) (Standard) [65513-72-6]
  • Delivery Days Customer
    5
  • CAS Number
    65513-72-6
  • Category Supplier
    CHEMICAL,detergents_surfactants
  • Certification
    Research Use Only
  • Molecular Weight
    409.26
  • Scientific Description
    Glafenine (hydrochloride) (Standard) is the analytical standard of Glafenine (hydrochloride). This product is intended for research and analytical applications. Glafenine (Glafenin) hydrochloride is a non-selective, non-steroidal anti-inflammatory drug-based COX-1/COX-2 inhibitor. Glafenine hydrochloride exerts anti-inflammatory, anti-proliferative and anti-cell migration effects by inhibiting the arachidonic acid metabolic pathway and reducing prostaglandin synthesis. Glafenine hydrochloride can induce cell cycle arrest in vascular smooth muscle cells and endothelial cells and reduce the synthesis of the extracellular matrix protein Tenascin. Glafenine hydrochloride can be used in the research of inflammatory-related diseases, vascular restenosis and cystic fibrosis (CF)[1][2][3][4].
  • SMILES
    [H]Cl.O=C(OCC(O)CO)C1=CC=CC=C1NC2=CC=NC3=CC(Cl)=CC=C23
  • UNSPSC
    12352100