Glecaprevir

AbMole BioScience

Glecaprevir

9

1365970-03-1

Chemical

Research Use Only

C38H46F4N6O9S

838.87

Glecaprevir is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that targets the the viral RNA replication. It displays IC50 values ranging from 3.5 to 11.3 nM for clinical isolates of HCV genotypes 1a, 1b, 2a, 2b, 3a, 4a, 5a, and 6a.

CC(C)(C)C1NC(=O)OC2CCCC2OC\C=C\C(F)(F)C3=NC4=C(C=CC=C4)N=C3OC5CC(N(C5)C1=O)C(=O)NC6(CC6C(F)F)C(=O)N[S](=O)(=O)C7(C)CC7

12352200