Gliovirin [83912-90-7]

TargetMol Chemicals

Gliovirin [83912-90-7]

999

83912-90-7

Chemical

Research Use Only

Gliovirin

C20H20N2O8S2

480.51

Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decreases phorbol 12-myristate 13-acetate (TPA)- and ionomycin-induced increased expression of COX-2 (IC50= 1 microM) and protein levels of IL-2 in Jurkat cells (IC50= 5.2 microM).1

3 years

COc1ccc(C2SSC34CC56OC5C=CC(O)C6ON3C(=O)C2NC4=O)c(O)c1OC

-20°C

12352200