Globalagliatin [1234703-40-2]

MedChem Express

Globalagliatin [1234703-40-2]

9

1234703-40-2

Research Use Only

98.0

C28H37N3O3S3

559.81

Globalagliatin (LY2608204) is an orally active glucokinase (GK) activator with an EC50 of 42 nM. Globalagliatin also stimulates glucose metabolism in rat insulinoma INS1-E cells with EC50 of 579 nM. Globalagliatin targets both pancreatic beta-cells and hepatocytes. Globalagliatin is promising for research of type 2 diabetes[1][2][3].

O=C([C@@]1(C2=CC=C(S(=O)(C3CC3)=O)C=C2)[C@H](C4CCCCC4)C1)NC5=NC=C(SCCN6CCCC6)S5

-20°C,2°C to 8°C

12352200