Chemical Structure
Globosuxanthone A [917091-74-8]
AG-CN2-0174
Overview
- SupplierAdipoGen Life Sciences
- Product NameGlobosuxanthone A
- Delivery Days Customer10
- CAS Number917091-74-8
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationWarning
- Molecular FormulaC15H12O7
- Molecular Weight304.3
- Scientific DescriptionChemical. CAS: 917091-74-8. Formula: C15H12O7. MW: 304.3. Isolated from fungus (species unknown). Potent anticancer agent. Inhibits cell growth, proliferation and survival of human tumor cells lines in vivo and in vitro. Exhibits strong cytotoxicity against a panel of human solid tumor cell lines, disrupting the cell cycle leading to the accumulation of cells in either G2/M or S phase and inducing classic signs of apoptosis. Antifungal agent against Candida albicans. - Potent anticancer agent. Inhibits cell growth, proliferation and survival of human tumor cells lines in vivo and in vitro. Exhibits strong cytotoxicity against a panel of human solid tumor cell lines, disrupting the cell cycle leading to the accumulation of cells in either G2/M or S phase and inducing classic signs of apoptosis. Antifungal agent against Candida albicans.
- SMILESOC1=C2C(OC(C=C[C@@H](O)[C@]3(C(OC)=O)O)=C3C2=O)=CC=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity: E.M.K.Wijeratne, et al.; Bioorg. Med. Chem. 14, 7917 (2006)
- Absolute Configurations of Globosuxanthone A and Secondary Metabolites from Microdiplodia sp.- A Novel Solid-State CD/TDDFT Approach: H. Hussain, et al.; Eur. J. Org. Chem. 2007, 292 (2007)
- A new dibenz[b,e]oxepine derivative, 1-hydroxy-10-methoxy-dibenz[b,e]oxepin-6,11-dione, from a marine-derived fungus, Beauveria bassiana TPU942; H. Yamazaki, et al.; Mar. Drugs 10, 2691 (2012)
- Dihydroxanthenones from the fermentation product of an endophytic fungus Gliomastix murorum: H.Y. Yang, et al.; J. Asian Nat. Prod. Res. 17, 319 (2015)