GLP1R antibody [HL2298]

GTX638353
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetGLP1R
Overview
- SupplierGeneTex
- Product NameGLP1R antibody [HL2298]
- Delivery Days Customer9
- Antibody SpecificityThis antibody was raised against human GLP1R Extracellular domain.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL2298
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID2740
- Target nameGLP1R
- Target descriptionglucagon like peptide 1 receptor
- Target synonymsGLP-1; GLP1 receptor; GLP-1 receptor; GLP-1R; GLP-1-R; glucagon-like peptide 1 receptor; seven transmembrane helix receptor
- HostRabbit
- IsotypeIgG
- Protein IDP43220
- Protein NameGlucagon-like peptide 1 receptor
- Scientific DescriptionThis gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203