Bio-Connect

GLP1R Polyclonal Antibody

RD85172A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetGLP1R
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    GLP1R Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2740
  • Target name
    GLP1R
  • Target description
    glucagon like peptide 1 receptor
  • Target synonyms
    GLP-1; GLP1 receptor; GLP-1 receptor; GLP-1R; GLP-1-R; glucagon-like peptide 1 receptor; seven transmembrane helix receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203