IHC-Fr analysis of rat cerebellum tissue using GTX00632 GluR2 antibody. Note that some GluA2 positive fibers (horizontal arrow) that are probable Bergmann glial processes do not stain for GluA2. Panel A : Co-localization of GluA2 (green) and calbindin D28-K (red) in Purkinje cell dendrites (vertical arrow). Panel B : Calbindin D28-K Panel C : GTX00632 Panel D : The molecular and Purkinje layer (blue).
GluR2 antibody
GTX00632
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Other Application
Product group Antibodies
ReactivityMouse, Rat
TargetGria2
Overview
- SupplierGeneTex
- Product NameGluR2 antibody
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.6 mg/ml
- ConjugateUnconjugated
- Gene ID29627
- Target nameGria2
- Target descriptionglutamate ionotropic receptor AMPA type subunit 2
- Target synonymsAMPA-selective glutamate receptor 2; GluA2; GluR2; gluR-B; GluR-K2; glutamate receptor 2; glutamate receptor B; glutamate receptor, ionotropic, AMPA 2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene. [provided by RefSeq, Jul 2008]
- ReactivityMouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203