Gly-Cyclopropane-Exatecan [2414254-49-0]
HY-148696A
Overview
- SupplierMedChem Express
- Product NameGly-Cyclopropane-Exatecan [2414254-49-0]
- Delivery Days Customer10
- CAS Number2414254-49-0
- CertificationResearch Use Only
- Molecular FormulaC32H34FN5O7
- Molecular Weight619.64
- Scientific DescriptionGly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan (HY-13631), a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro[1].
- SMILESNCC(NCOC(C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O
- UNSPSC12131703