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Gly-Cyclopropane-Exatecan [2414254-49-0]

HY-148696A
MedChem Express
CAS Number2414254-49-0
Product group Chemicals
Molecular Weight619.64
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Gly-Cyclopropane-Exatecan [2414254-49-0]
  • Delivery Days Customer
    10
  • CAS Number
    2414254-49-0
  • Certification
    Research Use Only
  • Molecular Formula
    C32H34FN5O7
  • Molecular Weight
    619.64
  • Scientific Description
    Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan (HY-13631), a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro[1].
  • SMILES
    NCC(NCOC(C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O
  • UNSPSC
    12131703